| Secretary of State | William J. Bryan, 1913 Robert Lansing, 1915 Bainbridge Colby, 1920 |
| Secretary of the Treasury | William G. McAdoo, 1913 Carter Glass, 1918 David F. Houston, 1920 |
| Secretary of War | Lindley M. Garrison, 1913 Newton D. Baker, 1916 |
| Attorney General | James C. McReynolds, 1913 Thomas W. Gregory, 1914 A. Mitchell Palmer, 1919 |
| Postmaster General | Albert S. Burleson, 1913 |
| Secretary of the Navy | Josephus Daniels, 1913 |
| Secretary of the Interior | Franklin K. Lane, 1913 John B. Payne, 1920 |
| Secretary of Agriculture | David F. Houston, 1913 Edwin T. Meredith, 1920 |
| Secretary of Commerce | William C. Redfield, 1913 Joshua W. Alexander, 1919 |
| Secretary of Labor | William B. Wilson, 1913 |